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Small Grants RFA


Funding Opportunity Description

WVCTSI is accepting Pilot Project Funding applications for clinical and translational research focusing on, but not limited to, specific health areas of importance to West Virginia and Appalachia at large. Of note, projects with significant laboratory based components must have very clear delineation of the plan for translation of the research with impact on human health.

The National Institutes of Health (NIH) defines clinical research as: (1) patient-oriented research; (2) epidemiologic and behavioral studies; and/or (3) outcomes research and health services research.  

Per the NIH, translational research includes:

  • The process of making discoveries in the research laboratory or in preclinical studies that will have an impact on human health and may lead to the development of studies in humans
  • The process of applying discoveries generated during research in the laboratory, and in preclinical studies, to the development of trials and studies in humans;
  • Research aimed at enhancing the adoption of best practices in the community.
  • Cost-effectiveness of prevention and treatment strategies are also important aspects of translational science.

Spring 2019 Deadline:                 May 1, 2019


Applicants are encouraged to meet with the Investigator Development Manager prior to application submission.

Meghan Reeves, MPH                      304-293-6581



For all funding cycles, the budget is limited to a maximum of $5,000 in total direct costs with a performance period of six months. Each site is required to use the NIH PHS 398 detailed budget form (Form Page 4); NIH Forms.


Eligibility Information

  • Principal Investigator (PI) must hold a faculty appointment or equivalent at the time the award is announced. For the purposes of this RFA, these are individuals who can independently apply for federal or non- federal investigator-initiated, peer-reviewed Research Project Grants (RPG). Individuals holding postdoctoral fellowships or other positions that lack independent status are not eligible to lead pilot projects.
  • Note that Marshall University faculty members must hold an appointment in either the School of Medicine or the School of Pharmacy. Other Schools and Colleges at Marshall University are NOT currently eligible for WVCTSI Pilot grants.
  • All Early Stage Investigator (ESI) PIs must complete the one page attachment with signature from proposed mentor. The Mentorship Agreement Plan can be found here. Early Stage Investigator(ESI) Principal Investigators, as defined by the NIH as a new investigator who has completed his or her terminal research degree or medical or other professional residency—whichever date is later—within the past 10 years and has not yet been awarded a substantial, competing NIH research grant.


  • The Project lead for Pilot projects may not concurrently have funding from other IDeA Program award mechanisms (e.g. INBRE, COBRE).
  • Pilot projects may not overlap with other ongoing WVCTSI-funded projects.
  • Faculty named in the WVCTSI organization (i.e. program chairs and key personnel) are restricted from serving as PI on WVCTSI pilot grants, as well as prohibited from having funds directed to their labs or programs. However, such individuals may be included on pilot grants in supportive roles such as Co-Investigators, mentors, and consultants.
  • **No clinical trials allowed for this funding mechanism.


Per NIH guidelines, only one (1) resubmission is allowed for any given proposal. If you are planning on completing a resubmission, please contact the WVCTSI team prior to re-submitting your application.



PHS 398 Forms

Human Subjects - Enrollment Table

Submission Checklist

Clinical Trials Template