Biomedical Informatics Resources
Mission
The Biomedical Informatics program has been created to establish an informatics infrastructure to support clinical and translational research in West Virginia. Our mission is to transform the health and healthcare of West Virginians through leading-edge biomedical informatics technologies.
Development of State-Wide IDR
We are currently developing a state-wide integrated data repository (IDR) that is bringing clinical information together into one centralized database from sources throughout the state. The IDR contains de-identified clinical information and will allow researchers to select patients suitable for clinical trials.
Currently we have started importing patient information from WVU Healthcare's Medsite and Epic (Merlin) systems. Eventually patient data will be imported from other clinical sources residing at WVCTSI participating institutions.
The first user application that we will make available for WVCTSI researchers is called i2b2 (informatics for integrating biology & the bedside). i2b2 is an open source database application that has been developed under the auspices of NIH. i2b2 has been installed on a WVCTSI server here and it connects to the WVCTSI IDR to query information within that database and return results to the user.
Data from the live IDR database is not yet accessible for research purposes, but in the meantime we have deployed a demo version of the i2b2 application that contains sample patient data. If you are a researcher and are interested in seeing the functionality that will be made available to you soon to support your research efforts, please test out the i2b2 demo application below.
WVCTSI I2B2 DEMO SYSTEM - TRY IT!
http://i2b2demo.wvctsi.org
username: demo
password: demo
Begin by selecting any criteria of interest from the ontology tree in the upper left and add them to the “groups” area on the right side of the screen. Once you have chosen your criteria, click the “run query” and a patient count will be returned. Please remember that demo data is being searched, so only basic criteria will return results.
Training and Assistance
We also provide mentoring and training in health informatics to clinical and translational researchers. If you need assistance with your research, please contact Dr. Chen or Dr. Guo. , the Biomedical Informatics program’s co-directors (see below).
Assistant Director and Key Personnel
Dr. Lan Guo, BMI Program Assistant Director. With a Ph.D. in Computer and Information Science and B.S. in Biochemistry and Molecular Biology, her experiences span formal model-based software development and validation, statistical and computational modeling, bioinformatics, and C/T researches. She was awarded a $1M R01 (LM009500) from NLM, NIH to develop a novel computational framework for individualized clinical decision-making. Dr. Guo has been a Project Director for a center grant (P20RR16440) and recently awarded a $1M stimulus grant to combine gene expression profiles with population approach for lung cancer prognosis.
Office: WVU Cancer Center, HSS, Room 1844
Email: lguo@hsc.wvu.edu
Tel: (304) 293 8718
Jeff Cox, Director of Operations for Clinical Informatics. He has over 12 years experience developing and implementing clinical and financial applications for medical facilities. His previous experience with clinical Oracle database implementations is helping guide the development, implementation, and clinical integration of the CTSI's Intergrated Data Repository.
Office: WVU HSC, Room 5534
Email: jcox@hsc.wvu.edu
Tel: (304) 293 6850
Mike Denney, MA, has over 27 years of experience in building healthcare applications. In addition to successfully developing 11 different data interfaces within the WVU Healthcare environment, he has been a key member of development teams that have built highly successful order management and results reporting systems for several hospitals nationwide.
Office: WVU HSC, Room 5534
Email: mdenney@hsc.wvu.edu
Tel: (304) 293 0408
SERVICES AND CONTACTS